
Rational Design of Multifunctional Complex Molecular Architectures via Dynamic Covalent Chemistry
PhD Dissertation presentation exploring the systematic approach to creating complex materials through reversible chemical bonds.

Postdoctoral Researcher | Organic Chemist | Materials Scientist | Innovator
I am a chemist with advanced training in organic synthesis and materials science, specializing in the design and discovery of functional materials that address real-world challenges. My research brings together organic synthesis, polymer chemistry, and data-driven strategies to engineer covalent organic frameworks (COFs) and dynamic polymer systems with applications in energy, health, and environmental remediation.
A distinctive aspect of my work is the integration of Lean Six Sigma methodology into chemical research. By applying structured process improvement, I streamline laboratory workflows, reduce inefficiencies, and enhance reproducibility, accelerating the pace of discovery. This approach reflects my commitment to merging scientific creativity with operational excellence.
Currently, I am a postdoctoral researcher at the University of Massachusetts Lowell, where I continue to advance interdisciplinary solutions at the intersection of chemistry, materials innovation, and process optimization.
Postdoctoral Researcher, University of Massachusetts Lowell, (2025–Present)
Ph.D. (Organic Chemistry), University of Massachusetts Lowell, (2020–2025)
Dissertation: Rational Design of Multifunctional Complex Architectures via Dynamic Covalent Chemistry
Advisor: Prof. Olof Ramström
B.Sc. (Chemistry), University of Lagos, Nigeria (2014–2018, 4.90/5)
Thesis: Assessing a Triphasic Porous System for Phosphorus Removal from Laundry Effluent
Supervisors: Distinguished Prof. B. I. Alo & Dr. A. A. Abayomi

COFs are crystalline, porous polymeric networks constructed by linking organic building blocks with strong covalent bonds. I design COF materials with tailored pore structures and functionalities for applications such as gas storage, catalysis, and sensing.

In my MODEM project, I used a monofunctional modulator to direct the formation of imine-linked 2D COFs with enhanced crystallinity and porosity. I optimized parameters to suppress rapid nucleation and promote long-range order.

I exploit reversible organic reactions to build adaptive polymer networks. Recent projects include the synthesis of organogels that are self-healable, regenerable, and degradable, and the investigation of unprecedented macrocyclization pathways in dynamic systems.

I adapt Lean Six Sigma principles in scientific research using DMAIC and DMADV frameworks to streamline experiments and advance material development. Lean eliminates inefficiencies, while Six Sigma boosts precision and reproducibility. Together, they foster a structured workflow that elevates my research quality.
University of Massachusetts Lowell
2025
University of Massachusetts Lowell
2022 - 2024
National Organization for the Professional Advancement of Black Chemists and Chemical Engineers
2024 & 2025
DuPont
2024
University of Lagos
2018
Best Graduating Student in Organic Chemistry
Continuous professional development in process optimization, quality management, and specialized technical skills.
Council of Six Sigma Certification
2024
Foundation in Six Sigma methodology and quality management principles
Council of Six Sigma Certification
2024
Advanced understanding of DMAIC framework and process improvement
Biopharma Group (UK)
2025
3-Day intensive workshop covering product characterization, cycle development, scale-up, and advanced freeze-drying techniques
Ayinla, M.; Zhao, R.; Qi, Y.; Azzarito, S.; Che, F.; Ramström, O.
2025, In Review
In ReviewAyinla, M.; Qi, Y.; Azzarito, S.; Zhao, R.; Che, F.; Ramström, O.
2025, Manuscript
ManuscriptQi, Y.; Ayinla, M.; Yang, Z.; Ramström, O.
Chem. Eur. J. 2025, 31, e202404720
PublishedQi, Y.; Ayinla, M.; Clifford, S.; Ramström, O.
J. Org. Chem. 2024, 89 (2), 1091–1098
PublishedRaviranga, N. G. H.; Ayinla, M.; Perera, H. A.; Qi, Y.; Yan, M.; Ramström, O.
ACS Infect. Dis. 2024, 10 (11), 3842–3852
PublishedKaralius, A.; Qi, Y.; Ayinla, M.; Szabo, Z.; Ramström, O.
Chem. Eur. J. 2024, 30, e202402409
PublishedQi, Y.; Ayinla, M.; Sobkowicz, M. J.; Ramström, O.
Macromol. Rapid Commun. 2023, 44, 2300011
PublishedNigerian Society of Chemical Engineers (NSChE) Rivers/Bayelsa Chapter Technical Meeting
Virtual
DuPont GOLD Seminar at DuPont Experimental Station
Wilmington, DE
NOBCChE Conference
Atlanta, GA
NOBCChE Conference
Orlando, FL
ACS Fall National Meeting
San Francisco, CA
I am committed to mentoring and community service, guiding emerging scientists through research, leadership, and academic engagement.
Supervised undergraduate students in the synthesis and characterization of reticulated materials, emphasizing experimental design, analytical techniques, and sustainable materials development.
Mentored graduate students pursuing green and scalable synthesis of COFs, data-driven materials optimization, and dynamic covalent chemistry for environmental and energy applications.
Represented the graduate student community; Supported initiatives that promoted professional development, academic involvement, and student advocacy.
Launched the university's inaugural competition in collaboration with the Graduate School.
Evaluated candidates for the university's highest teaching recognition.
Reviewed research submissions for Sigma Xi IFoRE, IEEE-MIT URTC, Virginia Junior Academy of Science (VJAS), California Science & Engineering Fair (CSEF).
Insights into covalent organic frameworks, dynamic chemistry, Lean Six Sigma methodology, and the intersection of materials science with process optimization.

PhD Dissertation presentation exploring the systematic approach to creating complex materials through reversible chemical bonds.

Explored synthesis of novel, crystalline COFs using aniline as a monofunctional modulator to enhance structure.

Explaining self-healing and adaptive polymers enabled by reversible chemistry and their applications in sustainable materials.

Discussing how Lean waste-elimination and Six Sigma quality control can improve lab processes and accelerate discovery.

A reflection on resilience, community, and the power of shaping spaces beyond limits, delivered to the Class of 2025.

Exploring how green chemistry principles and process optimization can drive innovation in materials science.
Interested in collaboration, research opportunities, or have questions about my work? I'd love to hear from you.